http://toxicdolls.com/members/belieffile6/activity/ Activity feed for Vinding Wagner. Mon, 09 Nov 2026 22:28:27 +0000 https://buddypress.org/?v= en-US 30 hourly 2 ddf04813b510129bcb81ec645de88d43 http://toxicdolls.com/activity-2/p/61327/ Sat, 19 Jul 2025 07:26:54 +0000 Background Acquired lymphedema is a common consequence of cancer surgery. Fibrosis is one of the main causes of chronic lymphedema since it hinders lymphatic regeneration and this causes a significant decrease in lymphatic flow and accumulation of excessive protein-rich fluid. The transforming growth factor-β1 (TGF-β1) signaling pathway is known i…[Read more]

]]> 0 45a2822075d0163cfe4cc5aafc2e8559 http://toxicdolls.com/activity-2/p/59938/ Fri, 18 Jul 2025 07:36:58 +0000 RESULTS Pharmacological inhibition of p90RSK by FMK or inhibition of p90RSK with adenoviral vector encoding a dominant negative form of p90RSK suppressed TGF-β1-induced ECM accumulation and EMT in lung epithelial cells and fibroblasts. Interestingly, FMK significantly inhibited TGF-β1-induced Smad3 nuclear translocation and smad binding e…[Read more]

]]> 0 76245e20de734f9fbb699074ab352987 http://toxicdolls.com/activity-2/p/56878/ Wed, 16 Jul 2025 07:28:37 +0000 Combination of CP-31398 and defactinib, a FAK inhibitor, also achieved synergistic inhibitory effects and increased p53 with FAK dephosphorylation levels greater than the single treatment. These data indicated that a p53-activating CP-31398 achieved growth inhibitory effects in combination with a MDM2 or a FAK inhibitor and suggested a possible…[Read more]

]]> 0 9e05b81b99d2b0c95a0131284dbdd4c9 http://toxicdolls.com/activity-2/p/55503/ Tue, 15 Jul 2025 07:34:51 +0000 Cystic echinococcosis (CE) is common in Africa especially in northern and eastern countries where it is highly prevalent and mainly caused by Echinococcus granulosus sensu stricto and Echinococcus granulosus sensu lato (G6/7). In a recent epidemiological survey in Nigeria, the G6/7 genotype was reportedly responsible for the majority of CE…[Read more]

]]> 0 a46a34d267aa9792e33d4f0b35c01de1 http://toxicdolls.com/activity-2/p/53872/ Mon, 14 Jul 2025 07:18:13 +0000 idella kidney) cells indicated that VP4 activated the MyD88-dependent TLR pathway. Knockdown of VP4 obtained opposite effects. These results collectively revealed that VP4 interacts with RIG-I to restrain interferon response and assist GCRV invasion. This study lays the foundation for anti-dsRNA virus molecular function research in teleost and…[Read more]

]]> 0 fa52ed7ed0cea61b36ccfeb03786d710 http://toxicdolls.com/activity-2/p/50389/ Sun, 13 Jul 2025 07:32:45 +0000 Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success. Despite the translation of ProTide technology into the clinic, there remain unresolved in vivo pharmacokinetic and…[Read more]

]]> 0 88b5be71f68877d164cdd08d1ba06054 http://toxicdolls.com/activity-2/p/46680/ Sat, 12 Jul 2025 07:31:27 +0000 Motivated by the dynamics of particles embedded in active gels, both in vitro and inside the cytoskeleton of living cells, we study an active generalization of the classical trap model. We demonstrate that activity leads to dramatic modifications in the diffusion compared to the thermal case the mean square displacement becomes subdiffusive,…[Read more]

]]> 0 c16dd7b9979b4a07048b8d248fb21a17 http://toxicdolls.com/activity-2/p/43188/ Fri, 11 Jul 2025 07:22:57 +0000 We present an unusual case of liver involvement in monoclonal gammopathy with generalized crystal-storing histiocytosis (G-CSH).A bone marrow storage disease was diagnosed in a 79-year-old man with monoclonal gammopathy of uncertain significance (MGUS). The patient presented with pleural effusion, an osteolytic lesion of the humerus, and an…[Read more]

]]> 0 7afc25cd77687801467d8b472bcaab0c http://toxicdolls.com/activity-2/p/41835/ Thu, 10 Jul 2025 19:54:30 +0000 Posting photos reinforced urges to exercise and restrict food intake and anxiety. Editing photos without posting caused an immediate decrease in weight/shape concerns and a delayed decrease in sadness. DISCUSSION Results support a consistent and direct link between posting edited photos and ED risk factors, suggesting that this is not a harmless…[Read more]

]]> 0 bb0d1d3d7de3224324fcb37101251b2a http://toxicdolls.com/activity-2/p/41793/ Thu, 10 Jul 2025 19:20:49 +0000 0