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Donaldson Mouritsen posted an update 10 months, 3 weeks ago
Background The ongoing corona virus disease 2019 (COVID-19) pandemic is having a worldwide impact. Valuable information on the clinical characteristics of COVID-19 in pregnant patients with an autoimmune disease, such as systemic lupus erythematosus (SLE), is currently lacking. Methods Herein, we describe the clinical presentation of 2 pregnant patients with SLE and mild symptomatic COVID-19 infection. Results In both pregnant SLE patients, a watchful-waiting approach without initiation of treatment for COVID-19 was taken. Ziftomenib clinical trial No adverse outcomes were reported and both pregnancies resulted in healthy neonates born at term. In one patient we observed a flare in SLE disease activity, most likely attributed to discontinuing SLE treatment. Conclusion Our report highlights the importance of multidisciplinary collaboration between health care professionals as well as individualized treatment decisions during unprecedented periods such as the current COVID-19 pandemic. Discontinuation of immunosuppressive drugs during the acute phase of a COVID-19 infection should be considered on a case-by-case basis. Maternal treatment decisions should be in line with current recommendations for treatment of rheumatic and musculoskeletal diseases during COVID-19 infection and in line with treatment of COVID- 19 during pregnancy.The friction reduction mechanism of glycerol monooleate (GMO) was investigated under boundary lubrication with elevated temperature. Tribological performances were tested using reciprocating test rig by adding 5 wt.% GMO into Poly-alpha Olefin (PAO) base oil. Friction coefficient and wear were recorded during experiments. The used oil was evaluated by infrared detection after experiments. Results show that GMO could reduce friction coefficient at both low and high temperature. At elevated temperature, the friction coefficient of PAO-GMO blend climb up gradually, followed by a decrease tendency, and the wear increase gradually with temperature. The results of Quartz Crystal Microbalance show that the physical adsorption film plays the main role in friction reduction at low temperature. While at high temperature, the Infrared Spectrum and X-Ray Photoelectron Spectrum show that the GMO involves into the chemisorption with friction surface, producing Fe(OH)O and Fe3O4. The friction reduction mechanism of GMO transferred from physisorption to chemisorption, which reduced friction coefficient at both low and high temperature.
Family Medicine was introduced as a major undergraduate clinical rotation in 2016 after the medical college at Imam Abdulrahman Bin Faisal University revised its curriculum.
Assessing how students’ medical knowledge has improved post Family Medicine introduction to the revised medical school curriculum.
This was a cross-sectional epidemiological study among fifth year clinical medical students (n = 219). A pretest and post-test was distributed to all fifth year clinical medical students voluntarily during the period of October 2017 to May 2018. They were asked to rate the exam as well.
The mean exam grades were 25.52 (SD = 4.44) and 34.16 (SD = 5.76) for pre-rotation and post-rotation, respectively. There was a statistically significant difference between post and pre rotation exam grade for the overall sample (
(218) = 23.73,
< .0001) indicating that students had a statistically significantly higher exam grades post-rotation (M = 34.16, SD = 5.76) than pre-rotation (M = 25.52, SD = 4.44). Females had a statistically significantly larger difference in post-rotation and pre-rotation exam grade than males indicating that they improved more in the post rotation exam. It was found that nearly 60% (59.36%) of subjects considered the exam difficult before the rotation; however, only around 40% (40.18%) considered the exam difficult after the rotation.
Students benefited after taking the course of family medicine. This helps in advocating for both the importance of this specialty and for the university’s decision in incorporating family medicine as a major clinical rotation for undergraduates.
Students benefited after taking the course of family medicine. This helps in advocating for both the importance of this specialty and for the university’s decision in incorporating family medicine as a major clinical rotation for undergraduates.
Under-five morbidity is a significant public health concern in developing countries, and maternal intervention remains vital to achieving under-five optimal health.
The study examined the influence of maternal self-rated capability status (SCS) on under-five morbidity in Ibadan North Local Government Area (LGA), Oyo State, Nigeria.
The study interviewed 683 nursing mothers surveyed from 20 primary healthcare centers (PHCs) from 13th to 27th September 2018 in the LGA of study. We employed logistic regression models to examine the association of 4 domains of maternal SCS on under-five morbidity incidence controlling for the potential confounding effects of maternal, child, and household sociodemographic attributes.
Under-five children of mothers with poor status in the knowledge of child morbidity, experience-informed action, child morbidity exposure, and childcare vulnerability domains are, respectively, 497%, 323%, 400%, and 318% more likely to be at risk of morbidity than their peers born to mothers with good status. In addition, the odds of morbidity were lower for children born to women with more than 1 under-five children (AOR 0.49, 95% CI 0.27, 0.88), while the odds were higher for those from households that are food-insecure (AOR 3.16, 95% CI 1.31, 7.65) and dispose of wastes within the compound (AOR 2.67, 95% CI 1.31, 5.45) relative to children in the comparative categories.
Our findings revealed the significance of maternal SCS as a crucial pathway for understanding and reducing under-five morbidity. Community interventions should prioritize empowering nursing mothers with prevention and care information necessary to reduce the under-five morbidity burden at the community level.
Our findings revealed the significance of maternal SCS as a crucial pathway for understanding and reducing under-five morbidity. Community interventions should prioritize empowering nursing mothers with prevention and care information necessary to reduce the under-five morbidity burden at the community level.