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The World Health Organization declared the COVID-19 outbreak as a Public Health Emergency of International Concern on January 31, 2020. China was the first country to experience the challenges of controlling COVID-19. Therefore, the purpose of this study was to examine the experiences of Chinese nurses who countermarched to the outbreak city for medical support in the very first period of this global infection.

A qualitative study of phenomenological research design was used to describe the experiences of 10 Chinese nurses. Data were collected in February 2020 through in-depth interviews and analyzed by conventional content analysis methods.

Chinese nurses experienced different psychological stages, work pressure, and challenges. New concepts of nursing also emerged during their clinical care for COVID-19 patients.

The guidance synthesized from the Chinese nurse stories could give specific direction for a well-prepared global nursing workforce and high-quality patient care in the present and future epidemics. The worries about discrimination of COVID-19 patients’ needs to be addressed culturally and emotionally as a priority by health care workers when they care for COVID-19 patients.

The guidance synthesized from the Chinese nurse stories could give specific direction for a well-prepared global nursing workforce and high-quality patient care in the present and future epidemics. The worries about discrimination of COVID-19 patients’ needs to be addressed culturally and emotionally as a priority by health care workers when they care for COVID-19 patients.We use data from the 2014 China Longitudinal Aging Social Survey to examine the effect of attitudes toward aging on quality of life among older adults in China. We find that older people who experience psychosocial loss may be less satisfied with their life, and have more feelings of depression and loneliness. Compared to older women, older men have lower life satisfaction, and more depression and loneliness, though psychosocial loss has less of an effect on them. Older women who experience psychosocial loss are more likely to be dissatisfied with their life and feel more depressive and lonelier than their male counterparts. Among those who experience psychosocial loss, older people living in rural communities have a higher level of life satisfaction, while living in urban areas may counteract some of the positive impact of psychological growth on reducing the frequency of feeling depressed and lonely. Social policy can play a role in shaping constructive social/community environments to build more positive attitudes toward aging.This study was performed to evaluate the effect of a six-week nutrition education intervention on the nutrition knowledge, attitude, practices, and nutrition status of school-age children (aged 6-12 years) in basic schools in Ghana. Short-term effects of nutrition education training sessions on teachers and caregivers were also assessed. Pre-post controlled design was used to evaluate the program. Intervention groups had significantly higher nutrition knowledge scores (8.8 ± 2.0 vs. 5.9 ± 2.1, P less then 0.0001) compared to controls in the lower primary level. A higher proportion of children in the intervention group strongly agreed they enjoyed learning about food and nutrition issues compared to the control group (88% vs. 77%, P = 0.031). There was no significant difference in dietary diversity scores (4.8 ± 2.0 vs. 5.1 ± 1.4, P = 0.184) or in measured anthropometric indices (3.6% vs. 8.2%, P = 0.08). A marginally lower proportion of stunted schoolchildren was observed among the intervention group compared to the control group (3.6% vs. 8.2%, P = 0.080). Nutrition knowledge of teachers and caregivers significantly improved (12.5 ± 1.87 vs. 9.2 ± 2.1; P = 0.031) and (5.86 ± 0.73 to 6.24 ± 1.02, P = 0.009), respectively. Nutrition education intervention could have positive impacts on knowledge and attitudes of school children, and may be crucial in the development of healthy behaviors for improved nutrition status.Sunitinib is the most commonly used first-line therapy for the treatment of advanced renal cell carcinoma (RCC), but intrinsic and extrinsic resistance to targeted therapies dramatically compromise the benefit of clinical outcome. Dissecting the underlying mechanisms and discovering reliable predictive biomarkers are urgently needed in clinic. Etanercept mw Here, we discovered miR-885-5p was notably decreased after sunitinib treatment and associated with poor disease progression in clear cell renal cell carcinoma (ccRCC). In vitro and in vivo studies identified miR-885-5p inhibition contributed to sunitinib resistance. Mechanistically, sunitinib treatment reduced GATA1 expression, which in turn reduced its binding to MIR885 promoter and resulted in miR-885-5p downregulation in transcriptional level. In addition, PLIN3 was confirmed to be directly targeted by miR-885-5p and its upregulation significantly increased lipid droplets formation to decrease sunitinib sensitivity. Therefore, GATA1/miR-885-5p/ PLIN3 pathway may serve as a potential therapeutic strategy and a biomarker for sunitinib treatment in ccRCC.Transposable elements (TEs) are repetitive DNA sequences with the ability to replicate across genomes and generate mutations with major transcriptional effects. Epigenetic silencing mechanisms that target TEs to limit their activity, including DNA methylation, add to the range of gene expression variants generated by TEs. Here, using the iconic gene flowering locus C (FLC) as a case study I discuss the multiple ways by which TEs can affect the expression of genes and contribute to the adaptation of plants to changing environments.People may consent to sexual activity with a partner when they do not desire it (i.e., sexual compliance), and such behavior is particularly prevalent in women. Despite the negative consequences of unwanted sex, (e.g., guilt and poor health), few studies have considered those factors influencing sexual compliance. Attachment anxiety is characterized by overestimation of relationship threats and sensitivity to romantic rejection and rape myths are beliefs about rape that deny, trivialize, or justify sexual aggression and assault. In the present study both attachment anxiety and rape myth acceptance were hypothesized to influence perceptions of unwanted sex and personal experience of sexual compliance. Heterosexual women (N = 158) completed a series of online standardized self-report measures. Hierarchical multiple regressions were conducted to determine whether attachment anxiety and rape myth acceptance predicted women’s perceptions of unwanted sex (perpetrator blame, victim blame, no blame, compliance, confrontation, and ignore) and personal experience of sexual compliance, while controlling for participant age and length of their current romantic relationship.