Activity

ers. Further research should conduct to evaluate and to improve the quality of care in the study area.Decoction extraction procedure was implemented to regain phenolic compounds from C. citratus leaves. The extraction variables, solid/liquid ratio (2-5 g/100 mL), temperature (85-95 °C), and time (5-10 min) were assessed by central composite design for process optimization. Antioxidant activity (DPPH) and total polyphenol content (TPC) were monitored as responses. The TPC and DPPH were 71.98 ± 0.33 mg GAE/100 mL extract and 80.63 ± 0.49 mg TE/100mL extract respectively under optimal conditions (solid/liquid ratio = 5, temperature = 93.8 °C and time 11.3 min). The evaluation of phenolic compounds and volatile compounds of C. citratus extract at conditions for optimum extraction revealed that caffeic (20.81 ± 0.003 mg/100mL) and syringic acids (18.63 ± 7.390 mg/100mL) were the main phenolic compounds while citral and geraniol were the primary volatile compounds. The results achieved herein suits the potential use of C. citratus extract as natural source of antioxidant and aroma compounds that can be employed in e addition of the antioxidant property of the beverage. It is also rich in organic acids, the main being propionic acid, which is known to have antimicrobial activity primarily against bacteria and mold. The lemongrass extract can therefore, extend the shelf life of the beverage they are incorporated in and also the citral present in lemongrass has antimicrobial properties.

To compare

the effect of a toothpaste containing fluoride (F), calcium silicate (CaSi) and sodium phosphate salts to conventional toothpaste (NaF) on human enamel specimens submitted to erosive and abrasive challenges.

48 sound and 48 enamel samples pre-treated with 1% citric acid were divided into 4 groups (n = 12) Group 1- Non-fluoride toothpaste; Group 2- NaF toothpaste (1450 ppmF); Group 3- CaSi toothpaste (1450 ppmF; MFP); Group 4- Erosion only. The samples were subjected to pH cycling (3 cycles/day; 90s; 1% citric acid, pH 3.6) and to abrasion for 7 days. After the 1

and the last cycle, they were submitted to abrasion (15s, 1.5N load), using a brushing machine, soft toothbrush and toothpaste slurry (13; 15ml/sample) and then immersed in the slurry for 45s. Samples were immersed in artificial saliva between the challenges. Enamel loss was evaluated using profilometry on days 3 and 7. Data were analysed by ANOVA and Tukey’s test (p < 0.05).

For sound enamel at baseline, mean (±SD) enamel losgood potential of the former to help prevent erosive tooth wear.Methylguanidine, an originator of carcinogenic methylnitrosourea, has been found in many animal meats and processed stored food often in high concentration. The present study was designed to understand the multiple dose effect of N-methyl-N-nitrosourea (MNU), an end product of methylguanidine, in Swiss albino mice fertility as well as cancer induction. Accordingly, a total of five experimental groups of animal (female Swiss albino mice) were taken, considering group-I as vehicle control and group-II-V as treatment groups (whereas group-II-Vwere treated with single to quadruple doses of 50 mg/kg of MNU respectively in a three weeks interval). Selleckchem SKLB-D18 After accomplishment of MNU injection, each female mice was mated with male mice to check the fertility efficiency. The results of the study indicated that, mice treated with highest number of MNU doses were 42.85% less efficient in getting pregnant than the control mice. There were noted changes in body weight, food and water intake upon MNU-exposure compared to control group. A significant increase in cumulative weight of vital female organs like uterus and ovary were also observed in mice injected with quadruple doses of MNU (50 mg/kg) compared to control mice. The findings of the study suggest the direct effect of MNU in pregnancy, without any cancer incidence in the vital female organs of Swiss albino mice.Stunting, decidedly prevalent in Ethiopia, is a reduction of linear growth associated with a series of adverse consequences. However, little is known about its determinants and factors associated in Ethiopia and elsewhere. Therefore, this study aimed to determine major undelying factors associated with risk of stunting among under-five children in Ethiopia. We used the 2016 Ethiopian Demographic and Heath Survey (EDHS) data and analysed a total of 11,023 children aged 0-59 months’ data. Bivariate and multivariate logistic regression were fitted to identify key predictors and factors associated with stunting. Results show that, household and demographic factors such as maternal education (AOR 0.67, 95% CI 0.51, 0.89), wealth index (AOR 0.65 (0.54, 0.78), sex of child (AOR 0.78 (0.72, 0.85), possession of refrigerator (AOR 0.57 (0.36, 0.89), possession of television and others like twin birth, house main floor material, types of cooking fuel were significantly association with stunting. Among dietary factors, early initiation of breast feeding; feeding powdered or fresh milk (AOR 0.63 (0.52, 0.76); formula feeding (AOR 0.41 (0.21, 0.81); consumption of organ meat(s) (AOR 0.52 (0.32, 0.85) and beta-carotene rich fruits and vegetables were significantly associated lower odds of stunting. Antenatal care (ANC) follow-up, deworming during pregnancy (AOR 0.11 (0.02, 0.74), institutional delivery (AOR 0.64 (0.58, 0.71) and birth size (AOR 5.1 (1.64, 15.88) were among the health care factors associated with stunting of under-five children. In conclusion, stunting is modulated by several household, dietary and healthcare factors, both at household and community-level. Likewise; improving household income, women empowerment, dietary diversity among mothers and children and improving maternal health care system are critical to mitigate under-five stunting more rapidly.We determined whether the dietary supplementation with a commercial product (vegetable biocholine – VB) for Lacaune ewes at peak lactation would improve animal health and production as well as milk quality. We also determined the effects of VB as a feed additive. We used thirty Lacaune ewes at 30 days of lactation, allocated into three groups T0 (control, without VB), T5 (5 g of VB/animal/day) and T10 (10 g of VB/animal/day). T10 sheep had greater milk yield during the experimental period. T10 ewes had also a significantly lower feed conversion ratio than the other groups. Total solids concentration of milk was higher in T10 than in the other groups on day 20. The somatic cell count in milk was lower in ewes that consumed VB in the highest dose (T10) than in the T0 and T5 in days 15 and 20. Lower levels of lipoperoxidation (LPO) and of reactive oxygen species (ROS) were observed in milk from ewes fed with the VB supplemented diet on day 20, associated with increased levels of total antioxidant capacity and superoxide dismutase activity in milk.