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The dorsal and ventral length of the penis before and after straightening were compared. Results The dorsal length of penis (A) was 33-39(35.6±3.2) mm, the length of ventral length of penis before straightening (B) was 28-35 (29.8±2.8) mm and the length of ventral length of penis after straightening (C) was 32-38 (34.3±2.1) mm, which were measured during the first stage of operation, and the difference between B and C was statistically significant (P0.05). The degree of penile curvature at the time of erection was less than 15° by measuring with the side photos in all patients during 0.5 to 2.5 years of follow-ups with an average of 1.7 years. Conclusions Penile curvature due to the asymmetry of the cavernous bodies could be effectively corrected by simple incision of ventral tunica albuginea, which showed a good result of early follow-up. The effect of this surgery on ventral penile straightening could be verified by measuring and comparing the ventral and dorsal length of penis during surgery.Objective To investigate the novel genetic cause associated with hypospadias and the strategy for preventing offspring genetic defects in these patients. Methods In March 2019, a patient with gonadal dysplasia (hypospadias associated with cryptorchidism) was referred to Shanghai General Hospital. His secondary sex characters, level of sex hormones and the development of male reproductive system was assessed through physical examination, sex hormone examination, male reproductive system B-ultrasound and computed tomography (CT). Whole-exome sequencing (WES) was preformed to investigate the pathogenic genetic variations associated with hypospadias and cryptorchidism. Also, Sanger sequencing was conducted to verify the WES results in the pedigree. Semen analysis was used to assess the fertility of the proband and the SRD5A2 gene analysis of his spouse was performed to assess the risk of genetic defects in the offspring. Results The patient suffered from gonadal dysplasia (hypospadias associated with cryptorchidism). Physical examination showed an inverted triangular distribution of pubic hair, small penis and the volume of the testis was 8 ml. Sex hormone examination revealed the level of FSH, LH, Pituitary prolactin (PRL), estrogen (E(2)), testosterone (T), and sex hormone-binding globulin (SHBG) was 25.81 U/L, 10.84 U/L, 21.09 μg/L, 153 pmol/L, 16.95 nmol/L, and 36.15 nmol/L respectively. B-ultrasound and computed tomography (CT) showed left inguinal testis. Also, semen analysis illustrated that the volume was 0.05 ml and sperm concentrationT(p.Gln6Ter)] may be the primary cause of disorders of sex development.The prevalence and distribution of infectious diseases and occupational diseases in specific time and space is the result of the interaction between natural environment, social economy and other factors, its distribution pattern has spatial properties. Based on the assumption of independence, the traditional statistical methods ignore the spatial attributes of diseases and cannot analyze the spatial characteristics of diseases. On the basis of geographic information system, the spatial autocorrelation analysis can simultaneously analyze the spatial relationship and attribute value of diseases, explore the spatial dependence of disease data in different spatial units, and provide decision-making basis for the prediction and early warning of diseases such as occupational and infectious diseases, and the formulation and evaluation of prevention and control measures.Objective To identify and to analyze occupational exposure factors generating from production process in an enterprise processing waste electronic products, to provide scientific evidences for protection measures. Methods From June to October 2017, seven waste electrical and electronic product processing enterprises in a province were selected as the research objects. These seven enterprises all include refrigerator dismantling line, washing machine dismantling line, air conditioning dismantling line, TV/computer dismantling line, CRT cutting line. Some enterprises also have circuit board line, wet precious metal recycling line, plastic crushing line, plastic granulating line and other deep processing operations such as precious metal recycling of waste circuit board, waste plastic crushing and recycling. The data were collected by the methods of occupational health field investigation and occupational health testing, and the exposure level of occupational hazard factors was evaluated by combining the effect of the protective facilities of occupational health engineering. Results the main occupational hazard factors of waste electrical and electronic products treatment enterprises were dust, noise, heavy metal, flame retardant, mercury, fluoride, cyanide, sodium hydroxide, hydrochloric acid and nitric acid. 145 effective samples were obtained from heavy metal sampling, including 102 individual samples and 43 fixed-point long-term samples. Among them, 8 samples lead exceeded the standard, all occurred in the TV dismantling line. In addition to flame retardants, plasticizers, insecticides and other components can be detected by high-throughput qualitative analysis using liquid chromatography-time-of-flight mass spectrometry. Finally, 123 effective 8-h equivalent sound level values were obtained by individual noise detection, 86 of which exceeded the standard, with a rate of 69.9%. Conclusion there are potential occupational hazards in the process of dismantling waste electrical and electronic products.Objective To investigate occupational hazards in waste incineration power generation enterprises. Methods From May 2016 to September 2018, four garbage incineration power generation enterprises in different regions and scales were selected as the survey objects. Investigated and analyzed the types of occupational hazards, workplace distribution and occupational disease prevention facilities and the concentration (intensity) of major types of work and workplace occupational hazards were also improved Line detection and analysis. Ruboxistaurin molecular weight Results Silica dust could be seen in slag tank, slag sorting and crusher operation position. The concentration of silica dust in each workplace fluctuates within 0.3-1.1 mg/m(3). Both the concentration of silica dust in the workplace and the time weighted average allowable concentration (C-TWA) of dust exposure of dust exposed workers were detected, but none of them exceeds the requirements of the national occupational exposure limit. Carbon monoxide, ammonia, nitrogen dioxide, hydrogen sulfide, non methane total hydrocarbon, formaldehyde, hydrogen fluoride, hydrogen cyanide, hydrochloric acid, sodium hydroxide and ozone were detected, but all meet the requirements of national occupational exposure limit.