Toxic Dolls | Shields Bates | Activity

Shields Bates posted an update: 96 (95% CI 0.94 to 0.98)). Maternal age was not consistently […]

Sun, 29 Jun 2025 12:00:11 +0000

96 (95% CI 0.94 to 0.98)). Maternal age was not consistently associated with umbilical artery pulsatility indices or placental weight. Conclusions Young maternal age is associated with higher risk of third trimester uterine artery notching, whereas advanced maternal age is associated with a higher third trimester uterine artery resistance index,…[Read more]

Shields Bates posted an update: Background There is renewed focus on the complement system in […]

Sat, 28 Jun 2025 12:51:37 +0000

Background There is renewed focus on the complement system in the pathogenesis of schizophrenia. In addition to providing aetiological insights, consistently dysregulated complement proteins in serum or plasma may have clinical utility as biomarkers. Methods We performed a systematic literature review searching PubMed, Embase and PsycINFO for…[Read more]

Shields Bates posted an update: The immunological strategies employed by insects to overcome […]

Fri, 27 Jun 2025 12:20:00 +0000

The immunological strategies employed by insects to overcome infection vary with the type of infection and may change with experience. We investigated how a bacterial infection in the hemocoel of the African malaria mosquito, Anopheles gambiae, prepares the immune system to face a subsequent bacterial infection. For this, adult female mosquitoes…[Read more]

Shields Bates posted an update: Anti-HIV chimeric antigen receptors (CARs) promote direct […]

Thu, 26 Jun 2025 12:54:08 +0000

Anti-HIV chimeric antigen receptors (CARs) promote direct killing of infected cells, thus offering a therapeutic approach aimed at durable suppression of infection emerging from viral reservoirs. CD4-based CARs represent a favored option, since they target the essential conserved primary receptor binding site on the HIV envelope glycoprotein…[Read more]

Shields Bates posted an update: We conclude that iASPP integrates the NF-κBp65 and p53 […]

Wed, 25 Jun 2025 12:58:35 +0000

We conclude that iASPP integrates the NF-κBp65 and p53 signaling pathways and thereby regulates cell fate in response to TIS, leading to chemotherapy resistance. These findings suggest that iASPP inhibition might be a strategy that could help restore senescence in cancer cells and improve outcomes of chemotherapy-based therapies. Published under…[Read more]

Shields Bates posted an update: 2% of patients after 6 months of treatment (P less then […]

Tue, 24 Jun 2025 12:56:50 +0000

2% of patients after 6 months of treatment (P less then 0.0001). The mean MMS increased from 68.8 to 83.1 (P less then 0.0001). A decrease in steroid dosage ( less then 10 mg/day) was effective in 57.9% of treated patients. In all, 42.8% of patients experienced adverse events infections (21.4% of patients); infusion reaction (7%); bradycardia…[Read more]

Shields Bates posted an update: Background Although the prevalence of abdominal obesity and […]

Mon, 23 Jun 2025 11:41:30 +0000

Background Although the prevalence of abdominal obesity and metabolic syndrome has been widely studied in the adult population, little is known about it in children and adolescents especially in developing countries. This study aimed to determine the prevalence of abdominal obesity and metabolic syndrome among children and adolescents in Yazd…[Read more]

Shields Bates became a registered member

Mon, 23 Jun 2025 11:00:06 +0000