@changeloss3
Active 10 months, 3 weeks ago
Following influenza infection, rs2248374-G ERAP2 expressing cells may transcribe an alternative spliced isoform ERAP2/Iso3. This variant, unlike ERAP2-wt, is unable to trim peptides to be loaded on MHC class I molecules, but it can still dimerize with both ERAP2-wt and ERAP1-wt, thus contributing to profiling an alternative cellular […] View