@oceanblack54
Active 10 months, 2 weeks ago
Employing a palladium catalyst, a new multicomponent dearomatization reaction of arylamines, using carbon monoxide and propargylic acetates, is demonstrated for the production of bridged polycyclic lactams. hedgehog signaling Double annulation of the amino group’s ipso and para positions by this method leads to the formation of four new bonds: […] View