Activity

Pharmaceutical interventions aim to correct or prevent a drug-related problem (DRP) that might lead to negative clinical consequences and increase health care costs.

To identify variables associated with the provision of pharmaceutical interventions by clinical pharmacists during hospitalization.

In this retrospective cohort study, adult inpatients of the medical ward of the University Hospital of the University of São Paulo in São Paulo, Brazil, were followed from admission to discharge. Logistic regression models were used to evaluate the association between occurrence of at least 1 pharmaceutical intervention and the following baseline characteristics sex, age, Charlson comorbidity index, renal failure, electrolyte imbalance, hemoglobin, platelet count, and use of a nasoenteric tube, as well as the number, second-level Anatomical Therapeutic Chemical (ATC) code, and administration route of prescribed medications.

A total of 148 patients were included in the study, of whom 75 (50.7%) were men. The mdentification, at the time of admission and possibly before the occurrence of a DRP, of patients at higher risk of requiring a pharmaceutical intervention later during their hospital stay. To optimize patient care, clinical pharmacists should closely follow inpatients with electrolyte imbalance, polypharmacy, and/or use of systemic antibacterials.

The findings of this study could allow the identification, at the time of admission and possibly before the occurrence of a DRP, of patients at higher risk of requiring a pharmaceutical intervention later during their hospital stay. To optimize patient care, clinical pharmacists should closely follow inpatients with electrolyte imbalance, polypharmacy, and/or use of systemic antibacterials.

Drug-drug interactions (DDIs) may cause adverse drug events, potentially leading to hospital admission. Clinical decision support systems (CDSSs) can improve decision-making by clinicians as well as drug safety. However, previous research has suggested that pharmacists are concerned about discrepancies between CDSSs and common clinical practice in terms of severity ratings and recommended actions for DDIs.

The primary objective was to characterize the level of agreement in terms of DDI severity ranking and actions recommended between the local CDSS and pharmacists. The secondary objectives were to determine the level of agreement among pharmacists concerning DDI severity, to determine the influence of the CDSS on clinicians’ decision-making, and to review the literature supporting the severity rankings of DDIs identified in the study institution’s database.

This 2-part survey study involved pharmacists and pharmacy residents working at 1 of 4 health organizations within the Lower Mainland Pharmacy Serviepancies in terms of severity rankings and actions proposed to manage DDIs, particularly for severe and contraindicated DDIs. The current CDSS did not appear to have a large impact on clinical decision-making, which suggests that it may not be functioning to its full potential.

This study identified a gap between the local CDSS and clinical practice. There were discrepancies in terms of severity rankings and actions proposed to manage DDIs, particularly for severe and contraindicated DDIs. The current CDSS did not appear to have a large impact on clinical decision-making, which suggests that it may not be functioning to its full potential.South Korea has been evaluated as a country that is responding well to COVID-19. The Government of the Republic of Korea discloses where, when, and by which means of transportation people confirmed to have the virus have visited. Although disclosure of movement has contributed to flattening the curve and providing timely medical service, concerns about privacy infringement have also been raised. This article determines what factors influence privacy risk tolerance, looking specifically at threat severity, vulnerability, response efficacy, and response cost. We also provide implications for the preparation of better countermeasures for the government to implement.Medical IoT devices that use miniature sensors to collect patient’s bio-signals and connected medical applications are playing a crucial role in providing pervasive and personalized healthcare. This technological improvement has also created opportunities for the better management of personal health information. The Personal Health Information Management System (PHIMS) supports activities such as acquisition, storage, organization, integration, and privacy-sensitive retrieval of consumer’s health information. For usability and wide acceptance, the PHIMS should follow the design principles that guarantee privacy-aware health information sharing, individual information control, integration of information obtained from multiple medical IoT devices, health information security, and flexibility. Recently, blockchain technology has emerged as a lucrative option for the management of personal health information. In this paper, we propose eHealthChain-a blockchain-based PHIMS for managing health data originating from medical IoT devices and connected applications. The eHealthChain architecture consists of four layers, which are a blockchain layer for hosting a blockchain database, an IoT device layer for obtaining personal health data, an application layer for facilitating health data sharing, and an adapter layer, which interfaces the blockchain layer with an application layer. Compared to existing systems, eHealthChain provides complete control to the user in terms of personal health data acquisition, sharing, and self-management. We also present a detailed implementation of a Proof of Concept (PoC) prototype of eHealthChain system built using Hyperledger Fabric platform.Bilateral symmetrical fibrous palate hyperplasia is not a common case in the literature. The cause of this pathological change is not completely known. The development of hyperplasia may also be associated with a genetic mutation in the gingival soft tissue or gingival injury. We present a case of a 47-year-old patient who developed a formation that manifested bilaterally in the hard palate. see more After the excision, there were no histological elements in the material that indicated aggressive behavior of the formation. The clinical and histological diagnosis was the bilateral symmetrical palate hyperplasia, which is a very rare condition.