Puggaard Johannesen

ciated with significant deterioration in renal function from baseline. Although not powered for secondary outcomes, there were no statistically significant differences in osteoporotic fracture or AKI incidence between the groups.This study demonstrates a substantial and persistent anti-osteoporosis treatment gap in men and women ≥50 years old w…[Read more]

Chylous ascites refers to the accumulation of lymphatic fluid in the peritoneal cavity. The causes of chylous ascites are various, and commonly include traumatic injury and obstruction, which disrupt the lymphatic system. In addition, cardiothoracic surgery may injure the thoracic duct and lead to chylothorax. However, there are very few reported…[Read more]

Also, in silico predictions confirmed the appropriateness of these compounds as drug-like candidates.Salicylic acid is one of the potent pharmaceutical organic acids that have various applications in the medical field. It acts as a plant hormone and helps in plant’s growth & defence against pathogens. Beyond its numerous functions in plants, SA…[Read more]

Tumor- and T cell-intrinsic mechanisms of immune checkpoint inhibition (ICI) response were uncovered.Cancer cells with abnormal chromosome numbers were sensitive to spindle assembly checkpoint inhibition.Knockout of any of several noncanonical open reading frames (ORF) impaired cancer cell survival.The KRASG12C inhibitor sotorasib continues to…[Read more]