Wagner Basse

The study of pollutant concentration fluctuations and their connection to meteorological parameters involved the use of Pearson correlation to analyze the relationship between PM2.5, PM10, NO2, SO2 concentrations, temperature, rainfall, and wind speed, over 15 months, from January 2020 to March 2021. Rainfall’s substantial influence on pollutant…[Read more]

This study reveals that the introduction of EVs derived from Pkd1-/- mouse distal convoluted tubule (mDCT15) cells produces a considerable increase in extracellular ATP release within Pkd1-/- mouse inner medullary collecting duct (iMCD3) cells. Subsequently, when Pkd1-/- iMCD3 cells were exposed to EVs of Pkd1-/- mDCT15 origin, there was an…[Read more]

The pulmonology service was contacted regarding a 69-year-old female patient with no noteworthy past medical history, because a routine chest X-ray showed an effusion. Among her surgical history, a hysterectomy was recorded. When evaluated at the pulmonology clinic, the patient presented as asymptomatic, with their vital signs remaining stable.…[Read more]

By simultaneously targeting the PD-1/PD-L1 signaling cascade and activating the 4-1BB pathway, HK010 demonstrates synergistic antitumor activity, strictly dependent on the PD-L1 receptor, both in vitro and in vivo. When the dose of HK010 was decreased to 0.03 mg/kg, it maintained a significant antitumor effect in a humanized mouse model bearing…[Read more]

The sciatic nerve’s response to GsMTx4 application was a lessening of the mechanical hypersensitivity triggered by Yoda1. Analysis of our data reveals a significant presence of Piezo1 in neuronal and non-neuronal cells of the peripheral sensory system. Painful nerve injury, in turn, appears to be correlated with the activation of Piezo1 in…[Read more]

This study’s findings may reveal a new pathway to elevate EGCG levels in meat without compromising the gel-like texture of the meat products.

The escalating depletion of wild fish populations necessitates the exploration of alternative feed sources for farmed salmon. Given the potential for a lower carbon footprint, we examined the…[Read more]