Langhoff Lancaster

Histone acetyltransferases (HATs) are important enzymes that transfer acetyl groups onto histones and thereby regulate both gene expression and chromosomal structures. Previous work has shown that the activation of sirtuins, which are histone deacetylases, can extend lifespan. This suggests that inhibiting HATs may have a similar beneficial…[Read more]

In the present work, a hydrogen-free one-step catalytic fractionation of woody biomass using commercial β-zeolite as catalyst in a flow-through reactor was carried out. Birch, spruce, and walnut shells were compared as lignocellulosic feedstocks. β-Zeolite acted as a bifunctional catalyst, preventing lignin repolymerization due to its s…[Read more]

Boys were more active and less sedentary in all age-categories. The onset of age-related lowering or leveling-off of physical activity and increase in sedentary time seems to become apparent at around 6 to 7 years of age. CONCLUSIONS Two third of European children and adolescents are not sufficiently active. Our findings suggest substantial g…[Read more]

This was associated with meta-omics signatures characteristic of a microbiome adapted to a more oxygen-rich gut environment, enriched with genes associated with reactive oxygen species metabolism and lipopolysaccharide biosynthesis, and depleted in genes involved in the metabolism of milk carbohydrates. The synbiotic formula modulated expression…[Read more]

Relatedly, the efficacy of two forms of the QG, a liquid form and a dressing form, was demonstrated at wound sites in this study, with both forms promoting the development of granulation, including angiogenesis and collagen deposition. Thus, the simply fabricated dual function nanocomposite presented herein not only offers reduced batch-to-batch…[Read more]

CONCLUSION Using a visual aid in consenting families for appendectomy does not add significant time and subjectively improves the process for providers and increases provider perception of parental understanding. LEVEL OF EVIDENCE Cost effectiveness, Level IV. Historically, human trichinellosis was caused by Trichinella spiralis and transmitted to…[Read more]

Phosphorus (P) has brought a series of environmental problems while benefiting mankind. To reclaim phosphorus from wastewater efficiently and conveniently, a novel magnetic adsorbent with aminated lignin/CeO2/Fe3O4 composites (AL-NH2@Fe3O4-Ce) possessing a high affinity to phosphate and easily separated from aqueous solutions was developed in this…[Read more]

e cement in service for 30 years with a lower occurrence of critical events.

A comprehensive bibliometric analysis to determine different aspects of the Journal of Prosthetic Dentistry is lacking.

The purpose of this bibliometric study was to analyze the characteristics of the Journal of Prosthetic Dentistry between 1970…[Read more]

health.The mitochondrial enzyme aldehyde dehydrogenase 2 (ALDH2) catalyzes the detoxification of acetaldehyde and endogenous lipid aldehydes. Approximately 40% of East Asians, accounting for 8% of the human population, carry the E504K mutation in ALDH2 that leads to accumulation of toxic reactive aldehydes and increases the risk for cardiovascular…[Read more]