McCall Munn

R-loop structures are a prevalent class of alternative non-B DNA structures that form during transcription upon invasion of the DNA template by the nascent RNA. R-loops form universally in the genomes of organisms ranging from bacteriophages, bacteria and yeasts to plants and animals, including mammals. A growing body of work has linked these…[Read more]

We reported the pharmacokinetic/pharmacodynamic (PK/PD) targets of a biosimilar generic product of amphotericin B colloidal dispersion (G-ABCD) againstCandida albicans (MIC 1-2 μg/mL) in a rat model of invasive candidiasis (IC) to facilitate its precision administration.

Single-dose plasma PKs of G-ABCD was studied in a rat IC model…[Read more]

The Healthy, Hunger-Free Kids Act of 2010 (P.L. 111-296) prompted the expansion of federal requirements for local school wellness policies, which aim to improve health promoting practices across school districts in the USA. This qualitative study examined how school district superintendents-as key school leaders who are often listed as the…[Read more]

With the emergence of several new epidemics of viral infections – SARS, MERS, EBOLA, ZIKA, Influenza A (H1N1) pandemic,Covid-2019 – over the past 3 decades we suggest that a world-wide programme of stratospheric surveillance and space weather monitoring should be urgently put in place without further delay.

To evaluate the first-attempt…[Read more]